Posts Tagged "Gerontology"
Engineered Negligible Senescence
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Welcome to Engineered Negligible Senescence. Engineered Negligible Senescence is a term attributed to Aubrey de Grey. Aubrey de Grey is an English author and theoretician in the field of gerontology, and the Chief Science Officer of the SENS Foundation. He is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007).
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De Grey’s research focuses on whether regenerative medicine can thwart the ageing process. He works on the development of what he calls “Strategies for Engineered Negligible Senescence” (SENS), a tissue-repair strategy intended to rejuvenate the human body and allow an indefinite lifespan. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage.
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This website is devoted to, of course, Aubrey de Grey! This biotech futurist is deserving of widespread support!
Video
Aubrey De Grey’s Seminar at Science World 2009 (part 4)
Dr Aubrey De Grey, author of the book Ending Ageing, explains in a clear, concise way in which it may be possible to add years onto the average life expectancy of a human being. Biological ageing is a progressive, degenerative process of decay. As ageing damage accumulates in our functional cellular and molecular structures, the healthy order laid down in our youth slowly falls apart. This damage occurs, as a result, of a series of unintended biochemical side effects of normal metabolism. As more and more of our cellular and molecular structures suffer this damage, functionality is lost, and health, resilience and vitality are slowly taken away from us, leading to increasing age-related pathology. Thus, metabolism causes ongoing ageing damage; this eventually accumulates to reach a critical mass at which it causes age-related frailty, disability, disease, and ultimately death. Aubrey looks at what approaches are already being taken eg in the areas of Geriatrics and Gerontology and introduces a third theoretical approach: SENS, which targets the damage of ageing itself, bringing it down to levels below the threshold at which it causes problems. www.fisher.co.uk
Anti-aging Medication
Aubrey De Grey’s Seminar at Science World 2009 (part 1)
Dr Aubrey De Grey, author of the book Ending Ageing, explains in a clear, concise way in which it may be possible to add years onto the average life expectancy of a human being. Biological ageing is a progressive, degenerative process of decay. As ageing damage accumulates in our functional cellular and molecular structures, the healthy order laid down in our youth slowly falls apart. This damage occurs, as a result, of a series of unintended biochemical side effects of normal metabolism. As more and more of our cellular and molecular structures suffer this damage, functionality is lost, and health, resilience and vitality are slowly taken away from us, leading to increasing age-related pathology. Thus, metabolism causes ongoing ageing damage; this eventually accumulates to reach a critical mass at which it causes age-related frailty, disability, disease, and ultimately death. Aubrey looks at what approaches are already being taken eg in the areas of Geriatrics and Gerontology and introduces a third theoretical approach: SENS, which targets the damage of ageing itself, bringing it down to levels below the threshold at which it causes problems. www.fisher.co.uk
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